Office 2016 for Mac is available through Microsoft Office 365 subscriptions for consumers and businesses. You Can Get It as Part of a Subscription or as a Standalone Product This is four times more memory than Office 2011 for Mac requires. To operate, Office 2016 for Mac needs 4 gigabytes of memory. It also requires 6 gigabytes of hard disk space in the Mac OS Extended Format (HFS+). Office 2016 for Mac requires Mac OS X 10.10 or a later version. Here are 10 things to consider if you are thinking about using Office 2016 for Mac: 1. This productivity suite aims to please the legions of Apple Macintosh users who have been clamoring for an update to Microsoft Office 2011 for Mac. Microsoft unveiled Office 2016 for Mac in July 2015.